Alzheimer’s begins during pregnancy

There is a disorder in the human brain that affects the abilities of the mind and it is called Alzheimer’s. Alzheimer’s over time affects more and more people and eventually causes forgetfulness. Alzheimer’s disease starts when the fetus is in its mother’s womb.

Researchers at the University of British Columbia have found that biochemical reactions in brain tissue that lead to Alzheimer’s disease begin when the fetus is in the mother’s womb.

The study, based on experiments performed on laboratory mice, found that vitamin A کم deficiency in the fetus or infant could trigger Alzheimer’s biochemical reactions, the Guardian reported on Saturday. Delivering vitamin A to infants can slow the progression of Alzheimer’s disease.

The researchers tested the effects of vitamin A deficiency in the womb and in the neonates of genetically engineered mice. As a result, it was found that mice that were deficient in vitamin A‌ during the fetal period showed poorer performance in educational processes and memory. In fact, a relative deficiency of this vitamin increases the production of a type of vitamin called beta amyloid in the body.

During Alzheimer’s disease, this protein forms plaques that kill neurons in the brain. Mice that were deficient in vitamin A in the uterus and received adequate amounts of this vitamin after birth also performed worse than normal mice. However, these mice performed better than mice that were deficient in vitamin A‌ in the mother’s womb and did not receive enough vitamin A after birth.

The results of this research clearly show that vitamin A deficiency, even in the early stages of pregnancy, has an adverse effect on fetal brain development and has long-term effects on health and may even lead to Alzheimer’s disease in adulthood.

Carrots, lettuce, potatoes, cod liver oil, red peppers, bell peppers, mangoes, mustard, walnuts, dried basil, tomatoes, apricots, peaches, spinach and beef liver are rich sources of vitamin A.

The full report is published in the journal Acta Neuropathologica‌.

source: Aftab

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