Complications of PCO and its treatments

How much do you know about polycystic ovary syndrome and what do you know about its treatment options?

Polycystic ovary syndrome (SPCO), sometimes referred to as ovarian laziness, is a common disease in women and is important because of the side effects it can have, often despite a family history. (Sister, mother, aunt, aunt, etc.) occurs and is actually a set of symptoms that can appear all of these symptoms in a person or only some of them manifest themselves.

Dr. Soheila Ansaripoor, obstetrician, gynecology infertility fellow and member of the specialized team of Ibn Sina Infertility and Recurrent Abortion Treatment Center, enumerating the most important symptoms of this syndrome, said: due to low and irregular ovulation or lack of ovulation for a long time For a long time, these people have delayed menstruation and sometimes even every few months, and due to the increase in male hormones, they suffer from excess hair growth or acne and hair loss. Glandular disorders in women of childbearing age, when the symptoms of this syndrome begin after puberty and the maximum age of onset is 20 to 40 years.

He added: “This syndrome is usually characterized by 2 signs of 3 signs of irregular menstruation, excess hair and the size of both sides of the ovary is full of small follicles. In fact, ovarian cyst means a small follicle containing 9-2 fluid.” It is a millimeter that is stable but does not require surgery at all, except in limited cases and during infertility.

He added: “Menstrual disorders (cycles less than 21 days or more than 35 days), is one of the most common complaints of these people and on the other hand one of the most common causes of menstrual irregularities in women of childbearing age (especially 20 to 40 years old). This is also the syndrome. In fact, any woman who presents with an irregular menstruation has polycystic ovary syndrome, unless proven otherwise.

Dr. Ansaripour continued: The treatment of the first line of medicine, for menstrual irregularities, of course, after lifestyle modification, both in girls (2 years after the start of the first menstrual cycle) and women, are the same contraceptive pills that must be taken Be a doctor’s opinion. Since this syndrome is a chronic disorder, the symptoms recur with discontinuation of the drug (its symptoms are not definitive but can be treated), so the pill should be continued intermittently, especially to prevent abnormal thickness of the uterine mucosa, but with weight loss. And following the right lifestyle increases recurrence intervals and also reduces complications.

Pointing to the importance of PCOS as one of the most important issues of infertility and also the general health of women, she stated: Obesity and especially abdominal obesity is seen in 2.3 patients with this syndrome and this is a scientific finding that most articles cite. Even if you lose 5 to 10 percent of your weight, you are more likely to resume ovulation and even get pregnant spontaneously. He emphasized that according to valid scientific recommendations and instructions, pregnancy in high weights, which is defined by BMI weight index (more than 30) with undesirable complications such as abortion and

Gestational poisoning and gestational diabetes are associated, so before attempting to conceive, these people should follow a nutritionist in addition to weight correction, healthy eating habits, exercise and even regular sleep.

A member of the specialized team of Ibn Sina Infertility Treatment Center, in expressing the complications of this syndrome, said: Possible complications include not ovulating regularly and therefore causing problems in pregnancy, irregular uterine bleeding and if left untreated, abnormal thickness of uterine mucosa and even the possibility of cancer. Uterine mucosa is older.
“In addition to the listed complications, such as abnormal and irregular uterine bleeding, even after pregnancy has occurred, there may be some early pregnancy complications such as miscarriage and recurrent miscarriage or late pregnancy complications such as gestational poisoning, gestational diabetes or Decreased fetal intrauterine growth appear. Other important side effects are cardiovascular problems, high blood pressure and sugar intolerance, type 2 diabetes, high blood fats and fatty liver, and low blood levels of vitamin D3. The risk of these complications increases with obesity and a family history. Patients with PCO syndrome should be evaluated for the risk of these complications by consulting a physician.

This study includes regular measurements of weight, waist circumference, blood pressure, blood sugar and lipid tolerance test, and other important complications of this syndrome include the possibility of depression and anxiety due to chronic problems and loss of confidence due to physical appearance, which unfortunately It distracts the person and therefore the person is in a vicious cycle, so these people need special attention.

Regarding the cause of this syndrome, Dr. Ansaripour said: “This syndrome has several factors, that is, in addition to the hereditary background, environmental factors are also involved.” One of the most important factors in your lifestyle, which includes eating habits, mobility, stress and even sleep cycle in these people. It is certain that the phenomenon of obesity increases the probability of its occurrence, and of course P.COS is also associated with obesity, especially abdominal and visceral fat.

He added: “The exact cause of this syndrome is not known and one of the causes is high blood insulin levels and in fact one of the underlying problems associated with PCO syndrome is the presence of hormone imbalance in women with polycystic ovary syndrome.” That is, the ovaries in these people produce estrogen and androgens (male hormones), or in other words, male hormones too naturally.

He also considered ultrasound to be the most appropriate method for early diagnosis and follow-up of polycystic ovary syndrome, adding: “Increasing the size of the ovary and the number of small cysts in each ovary and the more cysts, the more ovarian volume and disorders.” Clinically it becomes more obvious.

A member of the specialized team of Ibn Sina Infertility Treatment Center, while stating that PCO is not a disease but a syndrome in which the percentage of patients with it varies in different societies, emphasized: PCOS does not have a specific cause and its manifestations are variable, but if Neglecting this syndrome may manifest its side effects in the form of diseases such as diabetes and high blood pressure.
Regarding the effect of this syndrome on IVF cycles, Dr. Ansaripour added: “In obese people, a higher dose of gonadotropin is needed to stimulate ovulation, and during ovulation, easy access to ovarian follicles is reduced, and in thin people.” Excessive stimulation of the ovaries and therefore freezing of the fetus is more likely.
In both groups there is a possibility of reduced egg quality and also the probability of IVF failure, which of course is higher in obese people with PCO syndrome, so first of all adhere to a healthy lifestyle to prevent problems such as obesity and in the next stage, try to correct Healthy weight and eating habits are a serious and strict recommendation to these people.

Dr. Laden Giahi, a nutritionist and a member of the specialized team of Ibn Sina Infertility Treatment Center, said that before using any drug in the treatment of PCO syndrome, lifestyle changes are recommended as the first step in treating this disease. Improper eating habits that people have become accustomed to since childhood or adulthood and cause obesity and cause anxiety, depression, lack of self-confidence and نیاز need to be corrected.

Dr. Giahi further emphasized: The treatment of people with polycystic ovary syndrome requires a team and group therapy in the form of specialized counseling, in which the psychological and social issues of individuals should be fully considered.

He added: “If people with this syndrome have only 5 to 7 percent weight loss, their chances of fertility increase to 80 percent, which in turn reduces the amount of drug use and its side effects.”

The nutritionist pointed out that a patient with polycystic ovary syndrome, who needs to receive a diet, must be mentally prepared and properly counseled before any action is taken.

He added: “Severe fluctuations in blood sugar in patients with this syndrome is very important because it prevents people from losing weight by observing the intake of carbohydrates, amino acids, fatty acids and…, avoiding long-term hunger and Regulating blood sugar insulin levels is one of the most important issues that should be considered.

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