Consequences of a high cholesterol diet
Some foods have a great effect on increasing blood cholesterol. They also expose the body of consumers to colon cancer. If you want to avoid the risk of these complications, it is better to change your diet and prevent your excess weight.
The results of a new study show that high-cholesterol diets make cancer cells hyperactive and cause tumors to grow 100 times faster.
Cholesterol is a type of fat (lipid) in the blood. Body cells need cholesterol and all this need is produced in the body; But the body also receives cholesterol from food.
According to the Independent newspaper, in fact, cholesterol is an essential component of the outer membrane of all human cells and is produced in the liver as an essential building block for other important substances.
But high levels of cholesterol, especially bad cholesterol in the form of low-density lipoprotein (LDL), can have complications, including increasing the risk of heart attack or stroke.
Researchers at the University of California in the United States managed to explain for the first time the mechanism that allows fatty cholesterol to significantly increase the risk of colon cancer.
This study paves the way for the development of new drugs to prevent these diseases.
Researchers in this study found that cholesterol affects the growth of stem cells in the intestines and in turn increases the rate of tumor formation more than 100 times.
They noted that although the link between dietary cholesterol and colon cancer is well established, the mechanism involved was not known.
According to this report, health experts warn about the effect of consuming saturated fats on increasing cholesterol levels, and advise patients to avoid consuming foods such as fatty meat or cheese, and unsaturated fats found in nuts and avocados. to consume
Researchers in this study divided mice into two groups and gave one group a high cholesterol diet and genetically modified the mice in the second group so that their bodies naturally produce more cholesterol.
The researchers found that in both groups, excess cholesterol was a powerful inducer of intestinal stem cell (ISC) proliferation; Intestinal stem cells are responsible for intestinal growth.
As cholesterol levels increased, these stem cells divided faster, causing the intestinal tissue layer to increase in surface area and the intestine to become longer.
But this rapid growth also meant that the growth of tumor cells increased significantly.
Researchers still disagree about the ability of anti-cholesterol drugs such as statins to reduce the risk of colon cancers. Statins are widely prescribed to people at high risk of heart attacks or strokes.
This study was published in the journal Cell Stem Cell.
Irena
February 9, 2016 01:13
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