Principles of TB Control with Simple Methods

Unfortunately, today, due to preventive measures against tuberculosis, there are still many people who suffer from this complication. In order to deal with this dangerous disease, we need to inform and educate the people of the country in all parts of the world. They have named tuberculosis, so we will discuss ways to deal with this disease in this section.

March 24 has been designated World Tuberculosis Day to raise public awareness. This year’s slogan is the same as last year ‘Unity to end tuberculosis’

Tuberculosis is one of the top 10 causes of death worldwide and due to the increasing incidence of drug-resistant strains, attention to this disease is of particular importance.

March 24 has been designated World Tuberculosis Day to raise public awareness. This year’s slogan is the same as last year ‘Unity to end tuberculosis’.

Tuberculosis (TB) is an infectious disease caused by the bacterium Mycobacterium tuberculosis, which often attacks the lungs.
*** Facts published on tuberculosis by the World Health Organization
Tuberculosis is one of the top 10 causes of death worldwide.
In 2015, 10.4 million people were infected with tuberculosis and 1.8 million people died from the disease (of which 0.4 million were infected with HIV).
Between 2000 and 2014, about 43 million TB patients were saved from certain death by timely and effective diagnosis and treatment.
In 2014, 9.6 million people contracted tuberculosis and 1.5 million died.
About 95% of TB deaths occur in low- and middle-income countries.
In 2014, about one million children became infected with tuberculosis and 140,000 children died.
In 2015, about one million children were infected with tuberculosis and 170,000 children died from the disease.
Tuberculosis is the most important cause of death for AIDS patients. In 2015, one in three deaths from AIDS patients was due to tuberculosis
In 2014, about 480,000 people worldwide became resistant to the drug.
TB mortality has dropped by about 47 percent between 1990 and 2015.
– In 2015, about 480,000 people became infected with the multidrug resistant type.
Ending tuberculosis by 2030 is one of the goals of sustainable development.
Six countries – India, Indonesia, China, Nigeria, Pakistan and North Africa – account for 60% of TB cases.
*** The latest achievements in the treatment of tuberculosis
Researchers at Michigan State University recently used a drug to treat glaucoma to treat tuberculosis. These studies show that the ethoxzolamide compound used to treat glaucoma kills the ability of TB bacteria to grow in immune cells and shut down the infection. Preliminary results of this experiment on mice have been successful.
Studies by researchers at the University of Cambridge show that exposure to cigarette smoke and fossil fuels increases the risk of tuberculosis because it affects macrophages. The so-called macrophage has the same function as a vacuum cleaner and cleans and recycles all unwanted material and dead cells.
Macrophages are at the forefront of the immune system and are swallowed when pathogens enter the body, preventing the spread of infection.
The function of a macrophage is that when it encounters unwanted and harmful substances, it breaks them down and recycles them into a container called a lysosome. When the volume of material inside the lysosome increases, decomposition and recycling becomes difficult. Studies show that cigarette smoke blocks lysosomes and inhibits macrophages from fighting pathogens, increasing the risk of tuberculosis and the spread of infection in the body.
New studies show that curcumin in turmeric is effective in treating drug-resistant tuberculosis. Curcumin stimulates the immune system and a mechanism called apoptosis. This mechanism leads to the destruction of Mycobacterium tuberculosis using macrophages.
Given that tuberculosis is resistant to various drugs and is difficult to treat, its prevention and eradication requires careful planning by institutions and the government.

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