What role do genetic factors play in obesity?

the reason obesity And overweight is the entry of more calories into the body than the body’s metabolism. Obesity not only makes your body shape ugly but also endangers your health. The reason for endangering the body’s health is because obesity has a direct relationship with the main causes of death in the United States and around the world, such as: stroke, heart disease and diabetes, and all types of cancer. In this article from Hi doctor Want to about Causes of obesity Let’s talk with you dear ones.

Do genes play an important role in causing obesity?

In recent decades, obesity has become an epidemic in populations with an environment of physical inactivity and increased consumption of high-calorie foods. However, not all people living in such an environment will develop this disease, and not all obese people have the same distribution of body fat or suffer from the same health problems. These differences can be seen in groups of people with the same racial and ethnic background and even within families. Genetic changes that are responsible for the epidemic obesity disease And being overweight occurs very slowly in human populations. However, the difference is how people respond and are affected by the same environment and genetic factors that contribute to the occurrence of this chronic disease.

How can genes cause obesity?

Genes give instructions to the body to respond to changes in the environment. Studies of similarities and differences among family members, twins, and adopted children provide indirect scientific evidence that a significant portion of variation in weight among adults is due to genetic factors. Other studies have examined obese and non-obese individuals regarding variations in genes that can influence individual behaviors (such as the tendency to overeat or the tendency to exercise) or metabolism (such as the capacity to reduce the use of fat in the body). diet as fuel, or increasing the tendency to store fat in the body) have been compared. These studies have identified differences in several genes that may contribute to obesity by increasing hunger and food intake. Rarely, there is a clear pattern of inheritance of obesity in a family, caused by a specific variant of a single gene (monogenic obesity). Obesity is likely caused by a complex set of interactions among several genes and poorly understood environmental factors (multifactorial obesity).


“thrifty genotype” hypothesis

Any explanation in the epidemic of this disease is based on both genetic and environmental factors. One explanation is that there is a mismatch between today’s environment and the “energy-conserving gene” that existed in the distant past, when food supplies were unpredictable. In other words, according to the “thrifty genotype” hypothesis, the same genes that helped our ancestors survive occasional famines are now being challenged by environments with year-round food abundance. Is.

Can public health help genomics?

Currently, genetic tests for guidance diet Personal or physical activity programs are not helpful. Research into genetic changes that cause changes in diet and physical activity is still in its infancy. Doing a good job of explaining obesity in terms of genes and environmental factors can help motivate people who are trying to achieve and maintain a healthy weight are, help.

The effect of family history on obesity

Health care providers routinely take family health histories to help identify people at high risk for obesity-related diseases, such as diabetesThey collect and examine cardiovascular diseases and some types of cancer. Family health history reflects shared genetic influences among close relatives. Families cannot change their genes, but they can change the family environment to encourage healthy eating habits and physical activity. These changes can help improve the health of family members and improve the health history of the family in the next generation.

Information about obesity and overweight family members

Most health care providers use the Body Mass Index to determine if a person is overweight. You can calculate your body mass index (BMI) with a calculator. The calculation method is that you should divide your weight (in kilograms) by the square of your height (in meters).


Source: Red magazine

June 29, 2016 09:51

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